PMC 9207324
GGCT channels Gln flux for GSH synthesis and Glc anaplerosis into the TCA cycle ROS act as signaling molecules that regulate mitochondrial function, with mitochondrial morphology intrinsically linked to core processes, including the TCA cycle and oxidative phosphorylation
A total of 107 semen samples (23 ejaculates per dog) were analyzed for motilities and kinetic parameters, sperm concentration, total sperm count (TSC), acrosome and membrane integrity, morphological defects, DNA fragmentation, lipid peroxidation, and the enzymatic activities of superoxide dismutase, catalase, and glutathione peroxidase in spermatozoa and seminal plasma
This observation indicates that, at a certain level, GSH application can partly reverse the mutant phenotype
I., Siltelioglu Turan, I., Mammadov, R., Altnkaynak, K., & Kisaoglu, A
Glutathione infusion therapy delivers glutathione directly into the bloodstream through intravenous (IV) administration for enhanced absorption and bioavailability