The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed
ALA may rescue chemotherapy-induced mitochondrial toxicity to exert neuroprotective effects, but because of the differences in its in vivo experimental findings, future studies of ALA as a potential prevention of CIPN should not be ignored, while other exogenous antioxidant supplements, such as mineral elements, phytochemicals (curcumin and hesperidin), nutritional antioxidants, cytoprotectants and synthetic compounds, have very promising results in basic research
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Acetaminophen decreases intracellular glutathione levels and modulates cytokine production in human alveolar macrophages and type II pneumocytes in vitro
Therefore, new antidepressants with different mechanisms are needed to enable clinicians to diversify the treatment options for MDD