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Saxenda can cause a modest increase in heart rate (average 23 beats per minute), which requires monitoring in patients with pre-existing cardiac conditions
The skin benefit is notable because rapid weight loss can affect skin elasticity and health, making niacinamide a forward-thinking addition for people concerned about loose skin
The entire purpose of a control group is to isolate the supplement's effect from the natural effects of being in a study, receiving attention, and knowing your weight is being tracked
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