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Cancer cells often maintain intracellular GSH at 110 mM up to 1000 times greater than extracellular levels, which range from ~ 2 to 20 M [8]
Bauer DE, Hatzivassiliou G, Zhao F, Andreadis C, Thompson CB
This means that during postnatal development in diseased retinas, greater excretion of GSSG, into extracellular space where it get hydrolyzed, could lead to an increase in the [GSH]/[GSSG] ratio
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