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In summary, engineered GLP-1R-targeting nanoplatforms represent a transformative approach in the management of metabolic liver disease, enabling targeted delivery, enhanced pharmacokinetics, and multifunctional therapeutic capabilities that go beyond the limitations of conventional therapies
Las guas del American College of Physicians (ACP) priorizan los agonistas del receptor GLP-1 y los inhibidores de SGLT2 sobre las sulfonilureas debido a sus beneficios en resultados importantes para el paciente, aunque las sulfonilureas siguen siendo opciones en ciertos contextos clnicos
10.1038/ijo.2009.206 50 SemenkovichC.GoldbergI
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