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When citrulline is co-delivered intravenously with arginine, the result is a smoother pharmacodynamic curve, mitigating rapid peaks and troughs in vascular tone that otherwise accompany arginine-only infusions

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326 Under hypoxic or chemotherapy-induced stress conditions, mitochondrial transfer exhibits complex unidirectional or bidirectional transmission patterns

- Total fat mass : significant reduction in induced obesity models, without concomitant food intake reduction (the effect is truly energetic uncoupling via expenditure, not caloric restriction )

(13) DSIP and Longevity A study (14) was conducted on murine models, equally divided into DSIP and control groups

Then, the medication signals the brain to reduce appetite and slow gastric emptying