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Based on Phase 2 trial data (Jastreboff et al., NEJM , 2023), diarrhoea was reported in a meaningful proportion of participants treated with retatrutide, with incidence increasing in a dose-dependent manner
One limitation of this study is that potential changes in satiation during the treatment were not assessed
If you have high homocysteine levels you are likely low in methylcobalamin
Time 1 to 2 grams before workouts for acute support
Clarkson TW, Magos L
Factors that extend or shorten shelf life Extends shelf life: Proper refrigeration (consistent 2-8C) Minimal light exposure Sterile reconstitution technique Quality bacteriostatic water Sealed vial (rubber stopper intact) Shortens shelf life: Temperature fluctuations Light exposure Contamination during drawing Low-quality water Damaged vial seal Bottom line: 28-30 days is safe, conservative timeline for nearly all peptides when stored properly
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