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Any references to migration, angiogenesis, or tissue-related pathways are provided only for research context and do not imply therapeutic or clinical use

For weight management, NICE has appraised several licensed medicines that are available through NHS pathways or regulated private clinics: Semaglutide (Wegovy) NICE Technology Appraisal TA875 recommends semaglutide as an option for managing overweight and obesity in adults with a BMI of 35 kg/m or more (or 3034.9 kg/m in certain circumstances) alongside at least one weight-related comorbidity, when used within a specialist weight management service

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If patients do not tolerate the maintenance 2.4 mg once-weekly dose, the dose can be temporarily decreased to 1.7 mg once-weekly, for a maximum of 4 weeks

PREVIOUS EDITION IS OBSOLETE Date of Issue: 07/23 OPI-16 PRINCIPAL DISPLAY PANEL - 118 mL Bottle Label NDC 54482-148-01 CARNITOR SF (levocarnitine) Sugar-Free Oral Solution 118 mL (4 fl