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In a phase 2b trial, cotadutide reduced glycemia and body weight and improved metabolic-dysfunction associated steatotic liver disease (MASLD) 18

Ginger-based products (ginger tea or ginger biscuits) are commonly used as a complementary measure, though evidence for their efficacy in drug-induced nausea is limited

Avoid any rapid or extreme temperature changes

It should not be given to children or teenagers with or recovering from viral illnesses due to Reye's syndrome risk

In a recently published phase II trial, the effect of life style interventions along with increasing doses (0.3, 0.6, 1.2, 2.4 and 4.5 mg) of AM833 once weekly on body weight was investigated 706 individuals with obesity/overweight (140)

It is similar to rare cases caused by alpha-lipoic acid