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Its difficult to determine an A1C threshold at which you might change your mind about whether to use a GLP-1 receptor agonist to manage cardiovascular risk. 1 Post hoc results revealed consistent cardiovascular benefits across all BMI baseline categories, with more pronounced benefits in participants who had higher A1C levels at baseline

When will this be approved for weight loss

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Retatrutide delivered 24.2% average weight loss in clinical trials with 88.8% of participants completing the full 48-week study

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Future randomized trials should evaluate iron indices, hepcidin levels, ferritin, transferrin saturation, and hemoglobin trends in patients treated with GLP-1 receptor agonists