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Rare, but serious, adverse events associated with the intravascular injection of soft-tissue fillers in the face have been reported and include temporary or permanent vision impairment, blindness, cerebral ischemia or cerebral hemorrhage leading to stroke, skin necrosis, and damage to underlying facial structures

In such case, the Company may designate the shares of Common Stock that are to be treated as stock acquired pursuant to the exercise of Incentive Stock Options and the shares of Common Stock that are to be treated as stock acquired pursuant to nonstatutory stock options by issuing separate certificates for such shares and identifying the certificates as such in the stock transfer records of the Company

Abbreviations PCOS: Polycystic Ovary Syndrome IR: Insulin Resistance BMI: Body Mass Index LH: Luteinizing Hormone FSH: Follicle-Stimulating Hormone AMH: Anti-Mllerian Hormone GnRH: Gonadotropin-Releasing Hormone HG: Hyperinsulinemia ACTH: Adrenocorticotropic Hormone DHEA: Dehydroepiandrosterone DHEAS: Dehydroepiandrosterone Sulfate HOMA-IR: Homeostatic Model Assessment of Insulin Resistance HDL: High-Density Lipoprotein LDL: Low-Density Lipoprotein VLDL: Very Low-Density Lipoprotein TAC: Total Antioxidant Capacity GSH: Glutathione MDA: Malondialdehyde SHBG: Sex Hormone-Binding Globulin hs-CRP: High-Sensitivity C-Reactive Protein TRPV1: Transient Receptor Potential Vanilloid 1 EPA: Eicosapentaenoic Acid DHA: Docosahexaenoic Acid CoQ10: Coenzyme Q10 NAC: N-Acetyl Cysteine CrP: Chromium Picolinate RCT: Randomized Controlled Trial CC: Clomiphene Citrate LCKD: Low-Carbohydrate Ketogenic Diet GL: Glycemic Load GI: Glycemic Index PP: Premature Pubarche SCAD: Stable Coronary Artery Disease References Raveena, Rani et al

Diabetes trials use blood-sugar control, where tirzepatides GIP-driven improvement in insulin sensitivity is most visible. Results from one population do not transfer cleanly to the other

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