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Tirzepatide has demonstrated even more substantial weight loss in some trials, up to 20% of body weight, though it's worth noting this isn't strictly a pure GLP-1 medication

PMID: 41241376 Adnan SB et al

Patients should be counseled to seek immediate medical attention for severe, persistent abdominal pain, which may radiate to the back, with or without vomiting

It also appears to down-regulate glucocorticoids (stress hormones that promote muscle breakdown and inflammation), which adds another recovery-boosting layer to its profile

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Low levels of glutathione have been associated with oxidative stress