Thus, the olfactory nerve displays a direct connection between the brain and the nose, which could mediate the higher efficiency of nose-to-brain delivery via the olfactory mucosa compared to the respiratory mucosa [5]
Oxidative stress occurs when the body is overwhelmed by an excess of harmful molecules called free radicals, which it struggles to neutralise
Metabolomics and lipidomics datasets supporting the findings of this study are provided in Supplementary Table 12
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The obtained results showed the significant inhibition of protein and mRNA expression of TRPA1, IL-1, and TNF- by treatment with l-carnitine in comparison to the ACLT group