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Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice (in Eng)

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Mechanism of Action 5-Amino-1MQ inhibits NNMT, the enzyme that transfers a methyl group from SAM onto nicotinamide

Subsequently, for these data as well as the alpha diversity analyses, each treatment group (within each phylum or genus for the relative abundance data) was analyzed for normal distribution (ShapiroWilk test) and the data across groups were tested for homoscedasticity (BrownForsythe test)

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