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10.1056/NEJMe2202547 N Engl J Med
Avoid stimulant laxatives (senna, bisacodyl) as regular maintenance therapy, since chronic use can lead to dependence and reduced intestinal responsiveness
The prevalence of diabetes-associated microvascular complications across both cohorts was low (34%)
Currently, the treatment of invasive fungal infections relies exclusively on three main classes of antifungal drugs: polyenes, azoles, and echinocandins (Perfect, 2017)
Nishikawa, Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments
Understanding your genetic predispositions can help frame a more informed discussion with your provider about whether the additive benefit of combination therapy addresses your specific metabolic phenotype, or whether monotherapy or alternative agents might be more efficient for your genetics and lifestyle
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