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Independent testing across multiple vendors and compounds has revealed that weight accuracy issues are widespread
A pooled analysis of the STEP 1-3 clinical trials found nausea affected roughly 44% of participants on semaglutide 2.4 mg, with most GI symptoms mild to moderate and concentrated in the first weeks of treatment
Rare and serious side effects of Mounjaro include pancreatitis (inflammation of the pancreas), severe abdominal pain, hypoglycemia, serious allergic reactions, kidney problems, diabetic retinopathy complications, and gallbladder problems
Mechanisms include a decline in the level of thyroid hormones that promotes compensatory increases in TSH secretion from the pituitary gland