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L-carnitine may help support fat use without exercise, but is considered to be more effective when combined with physical activity

The concomitant administration of -tocotrienol has demonstrated an increased efficacy of gemcitabine (88), and a phase I study on pancreatic cancer patients was conducted with escalating doses of -tocotrienol in the 2 weeks before surgery (91)

According to the 2025 study on minimizing muscle loss, strength training and adequate protein were identified as key factors in maintaining muscle while losing weight on GLP-1s

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In addition, L-carnitine is being used as a supplementation therapy, and the best and safe combination with which therapy is used is a point to be considered in the future