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Every trial used a gradual step-up schedule, and that titration is the single most important factor in keeping side effects manageable
Patients were excluded if they had any other chronic liver disease other than MASLD/MASH including alcohol, viral, drug-induced, autoimmune, Budd-Chiari syndrome, Wilsons disease, alpha-1-antitrypsin deficiency, hereditary hemochromatosis, primary/secondary biliary cholangitis, primary sclerosing cholangitis, liver disorders in diseases classified elsewhere, and other chronic hepatitis not classified elsewhere
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Generally speaking, fatigue is a side effect that occurs when your body is adjusting to a "new normal" on the medication
When the applicator is positioned over the treatment area, it pulls your skin into the handpiece
You can take it even if you do not work out, but the results are more noticeable when paired with regular physical activity
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