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A blood test is the most reliable way to confirm whether B12 deficiency is a contributing factor

Regulatory agencies have warned about potential toxicity to the liver, kidneys, and nervous system

They are not for human consumption, therapeutic use, or medical application

The standard dose escalation schedule gradually increases doses to minimize side effects, but the first 8-16 weeks typically require the most vigilant hydration and prevention efforts

In a controlled crossover trial, Shang et al

Antiproteinuric response to dual blockade of the renin-angiotensin system in primary glomerulonephritis: Meta-analysis and metaregression