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However, in the lysosomal pathway, most acid hydrolases and Atp6v0d1 were downregulated

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In addition, these workers found that antidepressant treatment may lead to defective spindle assembly and altered organelle distribution, with changes in the protein concentrations of small C-terminal domain phosphatases-1 and -3, nuclear mitotic apparatus (NuMa), and calnexin occurring during cell division in vitro

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Archived from the original on 2018-03-23

At the 15 mg dose, 63% of participants lost at least 20% of their body weight, and 36% lost 25% or more