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It supports angiogenesis, tissue repair, and the modulation of transforming growth factor beta 1 (TGF1) signalinga pathway linked to amyloid plaque formation and tau pathology
Keywords 0 6 Introduction Alzheimers disease (AD) is a unique neurodegenerative disease causing progressive neuron damage in memory-associated structures, specifically neocortex, piriform cortex, hippocampus, locus ceruleus and the nucleus Basalis of Meynert
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Our findings indicate that hydrophobic interactions contribute more substantially to the interaction between the FOXO4 FHD and p53 TAD than electrostatic I nteractions
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