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There are only a few published cases of semaglutide use in PWS, usually in the setting of concomitant diabetes using doses of 0.5 and 1 mg weekly, with limited evidence on the long-term efficacy and safety of semaglutide in PWS without diabetes

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DNA and RNA oxidative damage and mortality of patients with COVID-19

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GLP-1 RAs have also demonstrated cardioprotective effects by reducing the risk of major cardiovascular events, such as heart attacks and strokes, in individuals with T2DM

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10.3390/ijms21155241 Int

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These usually improve within the first few weeks

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