Providers often recommend a structured transition plan because both medications affect digestion, appetite, blood sugar levels, and metabolic function
By comparison, Mounjaros pivotal SURMOUNT-1 trial reported up to around 22.5% mean weight loss at 72 weeks, and Wegovys STEP-1 trial reported around 14.9% at 68 weeks
Although, there is no clear evidence to suggest that the efficacy of semaglutide differs according to race or ethnicity, 67.1% of our participants were White
In terms of incoherence, the design-by-treatment interaction model did not identify global inconsistency in the analyses for both primary outcomes (ESM Tables 4 and 5), while local inconsistency was also low
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