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Patients with Crohn's disease require careful pre-operative assessment, as previous intestinal surgery, active inflammation, or malnutrition may affect surgical candidacy and outcomes

At 8 mg doses, the range was 17-60% depending on the specific trial and titration speed

The Wegovy FDA label carries a black-box warning for MTC risk in patients with a personal or family history of MTC or MEN2 [7]

Consider initial therapy at this stage when blood glucose 300 to 350 mg/dL (16.7 to 19.4 mmol/L) and/or HbA1C 10%-12% (86 to 108 mmol/mol), especially if the patient is symptomatic or if catabolic features (eg, weight loss, ketosis) are present, in which case basal insulin + mealtime insulin is the preferred initial regimen

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Vitals and symptom review to fine-tune dosing and timing