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These are pathway-level markers they do not predict response to semaglutide or any specific compound, but they frame the biology a clinician prescribes into

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Reactions vary between individuals: some may experience few or no side effects, while others may be more sensitive

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Searching for insulin-releasing peptides in the gut In the course of their research, Marks and Samols began to wonder whether the ingestion of glucose was due to an incretin-like substance originating from the gut which echoed with the incretin concept