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Pediatr Drugs 27 , 723734 (2025)

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Introduction Several studies have concluded that oxidative stress, due to increased production of reactive oxygen species (ROS), for instance, because of infection, can trigger inflammation, although the concept has been considered an oversimplification ( While in the context of oxidative stress GSH acts as an antioxidant ROS scavenger, in the context of redox regulation the couple GSH/GSSG (oxidized GSH) acts as a signaling molecule that regulates protein function via thioldisulfide exchange reactions including protein glutathionylation ( To investigate the role of endogenous GSH in inflammation, whether it acts as an antioxidant or a signaling molecule, we used the mouse macrophage RAW cell line stimulated with lipopolysaccharide (LPS) with and without pretreatment with the GSH synthesis inhibitor buthionine sulfoximine (BSO)

J Agric Food Chem 65(48):1038310394 Chen Y et al (2022) Mulberry leaf extract alleviates Staphylococcus aureus -induced conjunctivitis in rabbits via downregulation of NLRP3 inflammasome and upregulation of the Nrf2 system and suppression of pro-inflammatory cytokines

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Beschleunigt den Wundverschluss und untersttzt den natrlichen Geweberegenerationsprozess Schtzt Zellen vor oxidativem Stress durch Steigerung der endogenen Enzymaktivitt Beruhigt bermige Entzndungsreaktionen in verschiedenen Gewebesystemen Schtzt die Hautkeratinozyten vor Schden durch ultraviolette Strahlung Frdert die Angiogenese und verbessert so die Durchblutung und Nhrstoffversorgung des Gewebes