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Water retention or mild bloating: Small amounts of fluid retention can occur when starting peptide analogues of growth hormone because growth hormone causes sodium and water retention in the tissues, resulting in slight puffiness or bloating

Eichenbaum G, Wilsey JT, Fessel G, et al

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Nature 517 , 455459 (2015)

Its primary role here is to act as a chemical buffer to protect the BPC-157 peptide, not to provide a significant physiological effect of its own