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Review ArticleClinical Review The Journal of the American Board of Family Medicine May 2019, 32 (3) 431-447

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The glucagon receptor in retatrutide directly stimulates hepatic fat oxidation, creating a specific mechanism for liver fat reduction that dual agonists lack

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Es importante discutir con su mdico si: Ha ganado peso o su peso se ha estancado despus de una prdida inicial Sus niveles de glucosa en sangre permanecen consistentemente elevados Los efectos secundarios gastrointestinales no mejoran despus de 4-6 semanas Tiene dificultades para adherirse al rgimen de inyecciones Est considerando suspender el medicamento por cualquier razn Presenta signos de deshidratacin o problemas renales Su mdico puede realizar evaluaciones adicionales, incluyendo revisin de la tcnica de inyeccin, anlisis de laboratorio para descartar otras causas de resistencia al tratamiento (funcin tiroidea, niveles de cortisol), y evaluacin de medicamentos concomitantes que puedan interferir

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