Consider ease of use for end-users (patients or clinic staff) and overall durability
[1] [2] While high-dose oral B12 supplements can be effective through passive diffusion, they are not routinely recommended for pernicious anaemia management in UK practice
It is particularly common in individuals with certain risk factors, including those who have undergone gastric or small intestine resections, have inflammatory bowel disease, use metformin or proton pump inhibitors, follow a vegan diet, or are older than 75 years
I also inject B12 daily as I have severe neurological symptoms Subcut is definitely easier and far less painful
Always pick the vitamin B12 solution that allows you to dose easily
Some drugs, including proton pump inhibitors, metformin, and contraceptives, may affect vitamin B12 levels