Consider semaglutide if: You prioritize lower cost and established safety data You have a history of GI sensitivity and prefer gradual titration You want to start with the more affordable option (semaglutide at $299/month) You're seeking 15-18% weight loss with solid cardiovascular benefit Consider tirzepatide if: You have more aggressive weight loss goals (20%+ reduction) You have type 2 diabetes or significant cardiometabolic risk Cost is not a primary barrier You tolerate GI side effects well or are willing to manage them Many patients find success on either medication
If your primary problem is dry, cracked, structurally compromised skin: GHK-Cu addresses the barrier and collagen deficits
The NHS advises drinking no more than 14 units of alcohol per week, spread over three or more days, with several alcohol-free days each week
Ramos-Inza S, Almagro E, Font M, Enco I, Plano D, Sanmartn C, Sirera R, Lizarraga E
What GLP-1s are covered by Medicare
A higher-strength regimen may be considered when metformin has already been tolerated, but only within labeled limits