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Semaglutide is approved in multiple countries for type 2 diabetes and for chronic weight management at specific prescription doses and brands

Publishing them would invite exactly the kind of unsupervised self-administration that makes investigational peptides dangerous

Native amylin is notoriously difficult to work with because it aggregates to form amyloid fibrils (a property exploited by the pancreatic amyloid deposits seen in T2D progression)

& Erickson, C

Why use a non-inferiority margin instead of a competitive margin

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