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PLoSNegl Trop Dis 3:e457 Nathan ST, Mathew N, Kalyanasundaram M, Balaraman K (2005) Structure of glutathione S-transferase of the filarial parasite Wuchereria bancrofti: a target for drug development against adult worm

A high-resolution (2.0 A) structure of the enzyme in complex with S-hexyl glutathione in a new crystal form is presented

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When taken daily for 60 days, the synbiotic formula relieved constipation symptoms, improved bowel movement frequency, and improved quality of life scores more than placebo