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The next year, her family showed more concern, staging an intervention to ask her to give up her GLP-1s (via Page Six)

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On one hand, IBD can lead to dysregulation of adipokines, shifting the balance towards a pro-inflammatory state, on the other hand obesity and higher BMI are associated with higher risk of developing IBD and worse clinical outcomes, particularly for UC

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Peer review Peer review information Nature Metabolism thanks Darleen Sandoval and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

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If weight gain occurs, we can find alternative medications for treatment. Medications like carvedilol and nebivolol are often considered weight-neutral and are generally better options for patients who are particularly sensitive to this side effect, says Dr

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