Keep product in cool, dark place unmixed until needed
In addition, increased I 2 concentrations can also induce oxidative stress by increased activation of TPO ( 2 include augmentation of dendritic cell maturation, increase of T cells and antibody production by B cells, and increasing cytokine secretion ( via the Fas-mediated pathway and downregulation of Bcl-2, CD8 + T cell-mediated cytotoxicity by enhanced ICAM-1 expression increasing cellcell binding, and gap junction changes by downregulation of connexin 43
When this occurs in a stomach with delayed emptying, the increased fluid retention can compound nausea
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Atherosclerosis 315 , e117e118 (2020)
pmc.ncbi.nlm.nih.gov/articles/PMC5665799