During cellular stress, such as nutrient starvation and catabolic stress after trauma, surgery, infection, sepsis, or cancer cachexia, blood glutamine levels are severely decreased 144
JAMA 318 , 14601470 (2017)
Future investigations are required to establish therapeutic target for purinergic drugs in treatment of SZ patients
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In AD, glutamatergic and cholinergic synapses of the temporal lobe are affected first, followed by a spread to other regions (Picconi et al., 2005
It consistently pushes gene expression patterns away from disease states and toward healthier configurations