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10.1007/s00018-015-1937-8 211 TakeuchiS.WadaK.ToyookaT.ShinomiyaN.ShimazakiH.NakanishiK.et al
However, considering that the human bodys endogenous antioxidant system is not sufficient, the human body can hardly produce nonenzymatic antioxidants, so it depends on exogenous nonenzymatic antioxidants, such as mineral elements, nutritional antioxidants, phytochemicals, cytoprotectants and synthetic compounds (Table 1) [34, 36]
A pivotal RCT in 116 cannabis-dependent adolescents found that NAC (1,200 mg twice daily) more than doubled the odds of a negative urine cannabinoid test compared to placebo (OR 2.4, 95% CI 1.1-5.2) (Gray et al., Am J Psychiatry, 2012) [76]
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Lower oxidative stress: Daily glutathione cuts the GSSG-to-GSH ratio, which reflects less cellular damage
Symptoms of an allergic reaction may include swelling, rash, or difficulty breathing
