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The coverages of nifH and 16S rRNA genes in each metagenomic sample were calculated using Coverm v0.6.1 in contig mode ( (parameters: -min-read-percent-identity 80 (70 for the 16S rRNA gene) -min-read-aligned-percent 75 -methods reads_per_base) based on the customized nifH and 16S database described above

Treatment recommendations are individualised and based on clinical assessment, appetite response, and long-term sustainability rather than a one-size-fits-all approach

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However, over time (usually by 3 4 months) with continued treatment, skin lightens until you get the ideal complexion

Beyond these well-documented medical risks, a significant proportion of individuals with obesity present with psychiatric comorbidities, most notably depression and anxiety disorders [4], as well as eating disorders such as binge eating disorder (BED) [5]