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FLUIDS AND BARRIERS OF THE CNS, 22 (1)
Why Fluid Retention May Occur During Treatment Whilst water retention is not a documented side effect of semaglutide itself, several factors related to diabetes treatment and metabolic changes could potentially contribute to fluid accumulation or the perception of swelling during Ozempic therapy
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Broader pooled analyses across multiple trials show a similar pattern, at roughly 11.4% versus 7.3%, and a large real-world cohort study (Truveta) found about 11.2% versus 8.8% at 6 months
Compounded semaglutide is not Ozempic or Wegovy, and compounded tirzepatide is not Mounjaro or Zepbound
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