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consisting of mTOR, mLST8/GL, Rictor, and Sin1) regulating cytoskeletal dynamics and survival
Its active metabolite, fenofibric acid (FA), prevents apoptosis of retinal endothelial cells and maintains the blood-retinal barrier by preventing tight junction disorganization and hyperpermeability in diabetic conditions
doi:10.1007/s00415-020-10353-0
Table 3 Antioxidant therapy
In general, consistent with preclinical studies, RSV supplementation (500 mg/day, P.O for 4 weeks) raised erythrocyte PPAR- and Sirt1 expression and serum TAC and attenuated the total/HDL cholesterol ratio in CHD patients with type 2 diabetes [198]
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