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Second endpoints in REDEFINE 1 showed full benefits beyond weight loss

Neuroprotective effects in models of traumatic brain injury and spinal cord compression

This rapid improvement, while beneficial overall, can overwhelm already-damaged retinal blood vessels

Studies using the mouse Glp1r promoter to drive expression of a fluorescent reporter protein reveal Glp1r expression in the antral area of the stomach (near the gastric pylorus) as a fibrous signal that does not overlap with smooth muscle -actin (SMA) (Richards et al., 2014)

The variant, rs10305420, is a missense variant within the gene itself, meaning that it changes the protein encoded by the gene

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