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Combining with other medications that enhance effects Semaglutide taken alongside insulin or sulfonylureas carries an increased risk of hypoglycemia

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Of the 800 participants in the Effect of Semaglutide in Subjects with Non-cirrhotic Non-alcoholic Steatohepatitis (ESSENCE) trial, 534 were assigned to take semaglutide and 266 were in a placebo group: About 63% semaglutide users experienced a reduction in liver inflammation without worsening scarring, compared to only 34% of the placebo group