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In the future, single-cell sequencing technology could be used to further analyze the effects of GLP-1RAs on the cGAS-STING pathway and ferroptosis in different cell subpopulations, such as chondrocytes, macrophages, FLS, and neutrophils, in RA joints
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It's not an official diagnosis, but an informal term that refers to a potentially higher risk of eye problems and vision loss linked to GLP-1 drugs like semaglutide the active ingredient in Ozempic and Wegovy according to some recent studies
A clear dose-response relationship was established, wherein single doses of 0.3 and 1 mg/kg showed minimal efficacy, while significant tumor growth inhibition (TGI ~ 30%) was achieved at 3 mg/kg
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