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Parenteral thiamine can in rare instances trigger an acute allergic response characterized by hypotension, breathlessness, itching, and swelling
J Neurochem 36: 589593
Iron accumulation drives the Fenton and Haber-Weiss reactions, generating ROS that induce lipid peroxidation, leading to oxidative damage to subcellular structures (88)
Advancements in nanotechnology and molecular engineering will significantly enhance the bioavailability of repurposed drugs in CNS
Wynn, 2008
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