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In men, chronic insulin resistance reduces testosterone and sperm quality
So, without insurance, it can cost just as much as Wegovy
Clinical evidence comes in tiers: mechanistic studies (does the molecule do what it should at the cellular level?), animal studies (does it produce the expected effect in a living organism?), and human trials (does it actually work on the people who will use it?)
Circulation 1988;77:767-73
They work by mimicking the effects of GLP-1, a hormone the gut produces that regulates blood sugar levels
Joyce H, McCann A, Clynes M, Larkin A
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