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J Transl Med 23 , 1169 (2025)

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For maintenance , a monthly session may be enough

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Individual factors significantly influence how fluoxetine affects your weight, including: Your baseline weight and metabolic rate The severity of depression, anxiety, or eating disorder symptoms Dietary habits and physical activity levels Genetic factors affecting drug metabolism Concurrent medications It is important to note that weight changes associated with fluoxetine are generally modest compared to some other antidepressants