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It turned out that even with this (high) dose of somatostatin, insulin (and C-peptide) secretion was still slightly stimulated by GLP-1
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Collectively, these data showed that the most potently neutralizing antibodies were specific for the RBD 27,28,29,30,31,32,33,34 , but several strongly neutralizing antibodies also recognized the NTD 27,34,35,36,37 , and some were dependent on the quaternary assembly of the trimer 27,38
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These are not surrogate endpoints
Alternatively, some patients may reduce activity due to gastrointestinal side effects or fatigue, leading to deconditioning and subsequent discomfort when resuming normal activities
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