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Common early effects include reduced hunger between meals, earlier fullness, decreased portion sizes, and fewer food cravings

However, the quality of weight loss, whether from fat, muscle, or both, has become a key area of interest, particularly with long-term use

Sambri I, Massa F, Gullo F, Meneghini S, Cassina L, Carraro M, et al

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Currently, the majority of systematic reviews are devoted to the impact of GLP-1 receptor agonists on the effects on weight and metabolism causes, although there is still no systematic evidence of their psychiatric adverse effects [23].Specifically, since depression is a mental consequence with the low incidence rate and is affected by a variety of determinants, its evaluation demands higher level of statistical power and analysis of studies across different studies [24, 25]