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"The beneficial effects on cardiovascular health seem to be independent of weight loss," said Dr

In normal conditions, leptin prevents body weight gain by suppressing feeding (144, 145) and increasing energy expenditure (146148)

Those who take semaglutide for example, which is the active ingredient in Ozempic and Wegovy, can decrease their risk of heart attack, stroke and death by 20% after three years of treatment

First, the direct anti-inflammatory effects of GLP-1 receptor activation reduce inflammatory signaling independent of weight loss

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Alajeyan IA, Alsughayyir J, Alfhili MA