Nystrom and colleagues showed dose-dependent relaxation of femoral artery rings by GLP-1 in a rat organ bath model [113]
Interestingly, patients receiving tirzepatide report reduced overall GI AEs (40%), nausea (17.4%), diarrhea (13.2%) and vomiting (5.7%) compared to patients on semaglutide (43%, 19.2%, 13.7%, and 8.1% respectively)
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Oral supplements dont produce the levels you need to treat depression, so dont rely on OTC products
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