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However, the therapeutic utility of doxorubicin is undermined by its dose-dependent cardiotoxicity, possibly arising as a result of futile redox cycling, with NADH dehydrogenase within the mitochondria proposed as the most likely site of anthracycline reduction 9,10
IFN, Interferon
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In most cases this is a protective response
Most of the drugs undergo glucuronic acid conjugation and it is the most important amongst phase II metabolic reactions
